Combining global expertise with cutting-edge research pioneered by University Health Network’s Toronto General Hospital—a leading transplant center—Traferox Technologies Inc. is revolutionizing transplant care to help more people receive life-saving organ replacement.
X°Port
LUNG PRESERVATION SYSTEM WITH X°Port LUNG PRESERVATION SOLUTION
Storage, preservation, and transport of donor organs in an optimal temperature range, until the time of implantation
TorEx
LUNG PERFUSION SYSTEM WITH TorEx LUNG PERFUSATE
For continuous normothermic machine perfusion of donor lungs with unknown function, enabling ex vivo functional assessment for transplantation
Revolutionizing Transplantation End to End
X°PORT: Leverage the Power of 10°C for PRESERVATION AND TRANSPORT
Research shows that storing organs at 10°C optimizes preservation by slowing metabolic processes, preventing cell damage, and improving mitochondrial health. This temperature also helps maintain organ function during transport, allowing for improved logistics that benefit patients, surgeons, and hospitals.
TorEx: ASSESS VIABILITY OF LUNGS USING THE TORONTO TECHNIQUE FOR EVLP
The TorEx Lung Perfusion System enables the assessment of marginal donor lungs
using the Toronto Technique for EVLP (Ex Vivo Lung Perfusion). This process can help to assess viability for transplantation, even in lungs that would otherwise be discarded.
Transplantation of Assessed Lungs for expanded access to donor organs
With advanced assessment techniques like EVLP, clinicians can be more confident in the viability of the lungs they are transplanting, which can expand the donor pool and enhance access to transplantation.
Empowering clinicians to increase transplant volume through optimization of available organs
The Challenge: 80% of donor lungs are never transplanted1
Only 20% of donor lungs are accepted due to quality, logistics, and/or capacity concerns.
The Game Changer: 10°C
Lungs stored at 10°C have been transplanted after 24 hours of storage with no increase in complication rates compared to 6-hour storage at 4°C.2
EVLP with the Toronto Technique at Toronto General Hospital:
Increase transplant volume. Decrease operative mortality.
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- Smith, S., Trivedi, J.R., Fox, M. and Van Berkel, V.H., 2020. Donor lung utilization for transplantation in the United States. The Journal of Heart and Lung Transplantation, 39(4), p.S374. ↩︎
- Hoetzenecker K, Ali A, Campo-Cañaveral de la Cruz J, Schwarz S, Crowley Carrasco S, Romero Roman A, Aladaileh M, Benazzo A, Jaksch P, Wakeam E, Aversa M, Keshavjee S, Cypel M. Prolonged Preservation of up to 24h at 10°C does not Impact Outcomes after Lung Transplantation. Ann Surg. 2025 Jan 16. doi: 10.1097/SLA.0000000000006632. Epub ahead of print. PMID: 39817344. ↩︎
- Peel, J.K., Pullenayegum, E.M., Naimark, D., Aversa, M., Liu, M., Del Sorbo, L., Barrett, K., Sander, B. and Keshavjee, S., 2023. Evaluating the impact of ex vivo lung perfusion on organ transplantation: a retrospective cohort study. Annals of Surgery, 278(2), pp.288-296. ↩︎
- Ali, A., Wang, A., Ribeiro, R.V., Beroncal, E.L., Baciu, C., Galasso, M., Gomes, B., Mariscal, A., Hough, O., Brambate, E. and Abdelnour-Berchtold, E., 2021. Static lung storage at 10°C maintains mitochondrial health and preserves donor organ function. Science Translational Medicine, 13(611), p.eabf7601. ↩︎
- Hoetzenecker, K., Ali, A., de la Cruz, J.C.C., Schwarz, S., Carrasco, S.C., Roman, A.R., Aladaileh, M., Benazzo, A., Jaksch, P., Wakeam, E. and Aversa, M., 2025. Prolonged Preservation of up to 24 Hours at 10° C Does Not Impact Outcomes after Lung Transplantation. Annals of Surgery, 281(4), pp.664-670. ↩︎